What is IV NAD+ therapy?
During IV nicotinamide adenine dinucleotide (NAD+) therapy, NAD+ is administered through a vein (intravenously) in a standard saline solution. NAD+ is a coenzyme found in all cells of the body and is involved in a number of functions, including the production of energy in the mitochondria, DNA repair, cell survival, and metabolism. Research suggests that supporting NAD+ may be beneficial for those whose NAD+ levels are declining, a natural part of the aging process. NAD+ levels can also decline through things like oxidative stress and high-fat, high-sugar diets.

NAD+ Benefits for Your Health
NAD+ IV Therapy offers a wide range of benefits that can positively impact your health and quality of life. By replenishing the NAD+ levels in your body, this therapy can support cellular functions, slow down the aging process, and improve various physiological processes.

Here are some of the top NAD+ IV therapy benefits to know about.
1. Supports Cellular Health
NAD+ IV Therapy promotes cellular health through its direct impact on your NAD+ levels. By optimizing your cells’ NAD+ concentrations, this therapy can enhance your cellular energy production, support your DNA repair, and improve your overall cellular function. Additionally, NAD IV Therapy has been shown to boost the activity of sirtuins, which are proteins known to help regulate cellular processes and promote longevity. They also play a crucial role in various cellular functions, including aging, inflammation, metabolism, and stress response.

2. Enhances Energy and Performance
Whether you're an athlete, a busy professional, or simply seeking to boost your energy levels, NAD+ benefits your body in an attractive way by enhancing your energy and performance. By optimizing your cellular energy production, NAD+ IV therapy provides your body with the fuel it needs to perform at its best. In fact, people who undergo NAD+ infusions often report improved energy levels, mental clarity, and physical stamina.

3. Improves Brain Function and Cognitive Performance
NAD benefits extend to supporting brain health and cognitive function as well. In fact, research suggests that NAD+ plays a crucial role in DNA repair and the maintenance of neuronal integrity. By increasing your NAD+ levels, NAD+ IV therapy may even help to protect against neurodegenerative diseases such as Alzheimer’s and Parkinson's by helping to cool inflammation and slow down disease progression.

4. Cools Inflammation and Fights Oxidative Stress
It’s well established that chronic inflammation and oxidative stress are underlying factors in numerous health conditions. Fortunately, by reducing these factors, NAD+ benefits your overall well-being and helps to reduce the risk of diseases such as Alzheimer's, diabetes, and cardiovascular diseases. NAD IV Therapy contains anti-inflammatory and antioxidant properties, which help cool inflammation and fight oxidative stress in your body. Specifically, NAD+ molecules interact with certain proteins and enzymes involved in the inflammatory process, and this interaction helps to dampen the excessive immune response, which can lead to anything from allergies to autoimmune diseases including Hashimoto’s thyroiditis, Chron’s disease, ulcerative colitis, lupus, Sjögren’s syndrome, and more.

5. Promotes Healthy Aging and Longevity
One of the most notable NAD+ benefits has been in regards to its potential anti-aging effects. The steady decline we all experience in NAD+ levels is closely associated with the aging process. By replenishing NAD+ in the body, this therapy may help slow down the aging process and promote longevity. In fact, studies have shown that NAD IV therapy can enhance mitochondrial function, which is essential for cellular energy production and overall health. Research has shown that by supporting DNA repair mechanisms, enhancing mitochondrial function, and cooling inflammation, NAD IV therapy can help slow down the aging process and promote graceful aging.

6. Supports Cardiovascular Health
Another great NAD IV therapy benefit is that it has shown promising results in supporting cardiovascular health. As we’ve discussed, NAD+ enhances mitochondrial function in cells, and this is vital for energy production and maintaining a healthy heart and blood vessels. By optimizing cardiovascular function, this therapy can decrease your risk of heart disease, high blood pressure, and other related conditions.

7. Assists in Addiction Recovery
By restoring NAD+ levels in the body, NAD IV therapy has been shown to help reduce withdrawal symptoms, cravings, and drug-seeking behaviors for those recovering from addiction. This is largely due to its ability to optimize cellular function, which aids in both repairing the damage caused by substance abuse and promoting overall well-being during the recovery process. Often, NAD infusions are used in conjunction with other addiction treatment modalities to provide comprehensive support.

8. Enhances Immune System Function
Another significant NAD+ benefit is its ability to support immune cell activation, which helps your body fight off infections and diseases. By boosting your immune function, this therapy can improve your overall health and reduce the frequency and severity of illnesses, including those dealing with post-COVID and long COVID concerns. Specifically, NAD+ helps to activate immune cells, such as T cells and natural killer cells, and enables them to effectively target and eliminate pathogens. But that’s not all. NAD IV therapy also promotes cytokine production, which is essential for proper immune responses.

9. Supports Healthy Weight Management and Metabolism
Maintaining a healthy weight and a fast metabolism is crucial for overall well-being, but this can become harder as you age. Fortunately, NAD IV Therapy can support weight management and metabolism by optimizing the metabolic processes in your body. As you now know, NAD+ is involved in various metabolic reactions, including the conversion of food into energy. By enhancing your cells’ metabolic efficiency, NAD+ benefits weight loss efforts, increases your energy levels, and improves your overall body composition. In addition, NAD infusions help to regulate insulin sensitivity and support healthy blood sugar levels, a benefit that’s particularly helpful for those with metabolic disorders such as diabetes or insulin resistance.

Erin Buss, RN, BSN


Michael Buss, BS, NRP


Driftless Hydration

17 12th Street NE,
Rochester, MN


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